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It was found that 0.625-2.5 mg of intravenous (IV) droperidol showed statistically significant differences in the visual analog scale (on a line from 0 to 100, with zero corresponding to ‘no nausea’ and 100 to ‘unbearable nausea’) compared with placebo in 48 patients.134 Current evidence has shown that droperidol administration for CHS patients resulted in a shorter length of stay in the hospital, decreased necessity of other antiemetics (ondansetron and metoclopramide), and demonstrated a significant decrease in nausea severity from the baseline value, when compared with placebo.135 Benzodiazepines A case series of four treatment-resistant patients with CHS examined benzodiazepines (clonazepam) as a treatment option