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[16] [17] [18] [19] Mafireyi synthesized the first diselenide probe that was applied in the detection of TrxR

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However, the cleavage of pro-caspase-1 into active caspase-1 can be inhibited through the targeted inhibition of NLRP3 inflammasome activation, further blocking the transformation of the cytokine precursors pro-IL-1β and pro-IL-18 into bioactive IL-1β and IL-18, respectively