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Dysbiosis can compromise the intestinal mucosa barrier, allowing harmful metabolites like Trimethylamine N-oxide (TMAO) to enter the bloodstream, reach the liver, and contribute to chronic inflammation that damages the cardiovascular system (Shen et al., 2021)
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Indeed, in a 2015 review published in Medical Hypothesis, Discovery & Innovation , the authors concluded that SS-31 is “an attractive mitochondria-targeted antioxidant that can protect the mitochondria and RGCs against oxidative damage,” and designated it a “novel neuroprotective ophthalmic drug for protecting RGCs in glaucoma.”28 Many other studies have assessed SS-31 as a treatment for other ailments, including but not limited to osteoarthritis , hypertension , liver cancer , and heart failure