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CONCLUSION AND PERSPECTIVES The mitochondrial biogenesis is a complex biological process (Figure 1), that controls organelle's self‐renewal and the maintenance of mtDNA, ensuing cell homeostasis

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Unlike native IGF-1, this analog features a 13-amino acid N-terminal extension and an arginine substitution at position 3, conferring reduced affinity for insulin-like growth factor binding proteins (IGFBPs) and thus increased biological activity across multiple experimental models