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So often in practice, we may simply use a patients history and symptoms alongside a basic CBC (complete blood Count) and a short therapeutic trial of Vitamin B12 injections

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Well, normally this vitamin is absorbed in the gut and so a disruption to normal gut function will reduce the amount of vitamin B12 that's being absorbed by the intestines and that will lead to a depletion of the normal body stores, which will then result in a deficiency in this vitamin within the body as a whole