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The most pronounced change in the GSH/(GSH+GSSG) ratio is observed after 1 hour treatment at 37°C (from 87% to 73%) (Figure 2), partially reflecting the observed roGFP oxidation (Figure 1B)

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Ulcerative colitis is associated with impaired mucosal barrier function, which allows luminal bacteria to generate a prolonged and uncontrollable inflammatory response

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