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While HDAC inhibition can promote neurogenesis, complete loss of HDAC1 and HDAC2 in neural progenitor cells has the opposite effect, potentially preventing proper neuronal differentiation

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104 Myostatin, a key negative regulator of muscle growth belonging to the transforming growth factor-beta (TGF-β) superfamily, may become upregulated in the catabolic and disuse conditions that frequently follow ACL injury