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The Janus activated kinase (JAK)/signal transducer and activator of transcription (STAT) signalling pathway, stimulated by cytokines, is a cascade of multiple effects that plays a significant role in the immune system and immune response

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Puerarin mediates hepatoprotection against CCl4–induced hepatic fibrosis rats through attenuation of inflammation response and amelioration of metabolic function

One reviewer mentioned a gradual improvement over about two weeks