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Cumulatively, 20.9% of children with MASLD were diagnosed with a mental health condition over the study period: depression 13.6%, anxiety 12.6%, bipolar disorder 2.0%, obsessive compulsive disorder 0.7%, and schizophrenia 0.6%

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Conclusions Lactate, more than a product of metabolism, exerts modulating effects on the immune response and, depending on the cell type, could interfere or promote the inflammatory response