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doi: 10.1016/j.jacc.2013.11.005 [DOI] [PMC free article] [PubMed] [Google Scholar] 19.Dmitrienko A, Chuang-Stein C, D’Agostino R

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Animal studies administering 5-Amino-1MQ orally to diet-induced obese mice have shown dose-dependent reductions in body weight (typically 10-30% reduction compared to vehicle-treated obese controls over 4-12 week treatment periods), with the weight loss primarily reflecting fat mass reduction while lean mass is preserved or even increased