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For example, certain cancers cause upregulation of stress signals such as MHC class I chain-related protein A/B (MICA and MICB) and UL16-binding (ULBP16) family proteins, which are recognized by the activating NK cell receptor natural-killer group 2, member D (NKG2D), leading to direct killing (81)

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Consider ultrasound monitoring of amniotic fluid if NSAID treatment extends beyond 48 hours