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Mechanism in Tendon Repair BPC-157 promotes tendon healing through: VEGF upregulation — new blood vessel formation in avascular tendon tissue Growth hormone receptor activation — enhanced expression of GH receptor in tendon fibroblasts (Chang et al., 2014) FAK-paxillin pathway — promotes fibroblast migration and adhesion to injury sites Collagen organization — drives ordered collagen deposition over disordered scar tissue For complementary tendon healing through actin remodeling and angiogenesis, many researchers examine TB-500
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