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Several studies demonstrate that the pathological outcomes of the OS induction are involved in the development of many female reproductive diseases, including the PCOS, endometriosis, unexplained infertility, perturbation in oocyte quality, dysregulation of ovulation, and a decrease in the number of oocytes, as well as in the pregnancy complications, including recurrent miscarriage, pre-eclampsia, and IUGR (intrauterine growth restriction) [16, 17, 21]