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GHK-Cu exerts broad anti-inflammatory effects through its influence on approximately 31% of the human genome, specifically downregulating genes involved in inflammatory processes including interleukin-1β, tumor necrosis factor-α, and nuclear factor-κB (NF-κB) signaling while upregulating protective genes encoding antioxidant enzymes, DNA repair proteins, and anti-inflammatory mediators

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Physiological effects of L-theanine on Drosophila melanogaster