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The ligand stimulation of β-adrenoceptors activates the Gs subunit where the active α subunit binds to the adenylyl cyclase (AC) that converts ATP into cyclic 3′-5′-adenosine monophosphate (cAMP) [22], which in turn activates the cAMP-dependent protein kinase A (PKA), with a phosphorylation of serine/threonine residues of β-AR kinase (β-ARK)

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Size:0.68oz / 20ml

[DOI] [PMC free article] [PubMed] [Google Scholar] Zhang L., Hanigan M.H