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Sulfation (Safe Pathway) DECREASES 33% The Brookhuis 2021 data showed: “The estimated molar dose fraction of acetaminophen-sulphate decreased with the duration of pregnancy (24.2 (22.3–26.2%), 21.5 (19.9–23.1%) and 20.7 (19.1–22.4%) in the first, second and third trimester, respectively) compared with non-pregnant women (31.1 (29.0–33.3%)).”[⁶⁰] **This is a 33% DECREASE in the safe sulfation pathway by third trimester** (20.7% vs 31.1%)