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The treatment of IGF-1 lentivirus vectors Besides, to investigate the role of IGF-1 in liver fibrosis, the GFP-IGF-1-lentivirus vector and the GFP-blank vector were produced by Hanbio AdenoVector Institute (Shanghai, China) and the dose of 10 11 viral particles was injected through caudal vein to rats 1 week before the intraperitoneal injection of CCl 4 -olive oil solution