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The FDA placed BPC-157 on import alert, making it legally ineligible as a dietary supplement ingredient in the U.S

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demonstrated that metformin inhibits PDGF-induced phosphorylations, resulting in the inhibition of HSC proliferation and migration and a reduction in extracellular matrix secretions consisting of type I collagen and fibronectin, which leads to the inhibition of fibrosis [69,71]