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The compound did not demonstrate statistically significant weight loss compared to placebo over the longer treatment period

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The primary transcription factors that control the expression of the Mn-SOD gene are NF-κB, specificity protein 1 (Sp1), activating protein-1 (Ap1), p53, and CCAAT binding protein (C/EBP), which either directly bind to particular DNA regions or interact with its partners [15]