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Features that distinguish liposarcoma from a lipoma include: Rapid growth over a short period Hard or fixed lump (does not move) Pain without apparent reason Large size (usually greater than 5 cm) Deep location (under the muscle, not just under the skin) If you have any of these features, your doctor may recommend an ultrasound, MRI, or biopsy to rule out cancer

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The discovery of new lipolytic enzymes and coregulators, the demonstration that lipophagy and lysosomal lipolysis contribute to the degradation of cellular lipid stores and the characterization of numerous factors and signalling pathways that regulate lipid hydrolysis on transcriptional and post-transcriptional levels have revolutionized our understanding of lipolysis