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Because AHK‑Cu mainly targets the follicle cells themselves, and GHK‑Cu mainly supports the surrounding scalp tissue, using both can provide more complete support for crown thinning than either alone

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However, the toxin was present not only in other marine animals such as octopuses, gobies and sea stars, but also in phylogenetically unrelated terrestrial and aquatic organisms, including a dinoflagellate Alexandrium tamarense , red calcareous algae, arthropods, echinoderms, molluscs, worms, newts, frogs, and bacteria Actinomyces , Aeromonas , Alteromonas , Bacillus and Pseudomonas (Lago et al., 2015