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Along with the above mentioned lytic activators, several other cellular factors, such as XBP-1, CBP, the SWI/SNF chromatin remodeling complex, the TRAP/Mediator complex, RBP-Jκ, human Notch intracellular domain, and HMGB1, have been shown to promote KSHV reactivation and/or lytic gene expression (Liang et al., 2002
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Elevated Ca2 + at the triad junction underlies dysregulation of Ca2 + signaling in dysferlin-null skeletal muscle