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The increased bioavailability of reactive oxygen species (ROS) (termed oxidative stress) due to excess ROS generation, decreased nitric oxide (NO) levels, and reduced antioxidant capacity in the cardiovascular, renal, and nervous systems are common features of these processes (4, 5)
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Researchers first characterised the peptide in the early 1990s, and it’s since built up one of the most extensive bodies of preclinical literature in the field
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