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Consequently, the integration of advanced nanotechnologies, including microneedles, nanoliposomes, and nanostructured lipid carriers, appears critical for successful clinical translation [70,109,122]

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In erastin- or RSL3-induced ferroptosis in hepatocellular carcinoma cells, IFN-γ triggers the JAK-STAT-IRF1 axis and inhibits transcription of the System Xc− subunits SLC3A2 and SLC7A11 (122, 123)