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You may need a supplement if you: Eat a vegetarian or vegan diet and don’t consume enough foods that contain the vitamins Take heartburn medications Have had weight loss surgery Have a disease that affects your stomach lining or gut, such as IBD or Crohn’s disease Have or are at risk of getting age-related macular degeneration (AMD) Are older and don’t get enough B vitamins through your diet In many cases, you may not need a B complex supplement, but a single B vitamin supplement
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(63) identified single-nucleotide polymorphisms (SNPs) in genes encoding TNF-α, TGF-β1, IL-10, IL-6, and interferon γ (IFN-α), showing associations with disease severity and treatment response