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The AMPK Connection and Metabolic Flexibility MOTS-c operates primarily through the AMPK signaling pathway—the same master metabolic switch activated by exercise, caloric restriction, and metformin

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Although many publications dating back to the beginning of this century about antioxidants in general (and GSH in particular) only tend to underline the beneficial effects that these substances have in cancer patients, possibly preventing cancer onset and curing anticancer treatment adverse events, much more has been discovered in recent years, as widely displayed in this review