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Clinical Studies Dietary intakes of vitamin E in 178 men and women aged (70–96 year) indicated that intake of vitamin E may influence lung function by increasing FVC, FEV1 and showed protective effects on wheeze in elderly in three European countries including Finland ( n = 1,248), Italy ( n = 1,386), and the Netherlands ( In a placebo-controlled randomized clinical trial the effects of natural vitamin E (500 mg) or matched placebo in 72 participants aged (18–60 years) for 6 weeks, had no significant impact on FEV1, asthma symptom scores, or serum immunoglobulin levels ( The therapeutic effects of pharmaceutical drugs on SM-induced lung disorders in experimental and clinical studies were summarized in Tables 1, 2, respectively

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