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Treatment with ferrostatin-1 reversed these changes, suggesting the role of ferroptosis in ventricular hypertrophy (125)

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The team further discovered that Tan IIA acts against PH by up-regulating the expression levels of protein kinase G (PKG) and peroxisome proliferator-activated receptor γ (PPAR-γ) in pulmonary vascular smooth muscle and hypoxia-induced rat PASMCs in a hypoxia-induced rat PH model